Leukemia treatment break: study tests pausing chemo for AML patients

NCT ID NCT06511882

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether people with acute myeloid leukemia (AML) who have been on a combination of azacitidine or decitabine plus venetoclax for a year can stop treatment if tests show no remaining cancer cells. Researchers want to see if these patients can stay in remission without the leukemia returning. The trial will enroll 37 adults whose AML is in remission with no detectable disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

azacitidine or decitabine combined with venetoclax

What this could lead to

If successful, this could allow some AML patients to take a break from chemotherapy without their cancer coming back, improving quality of life.

What could go wrong

This is a small early-phase study with only 37 participants, so results may not apply to everyone. There is a risk that the leukemia could return after stopping treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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