Major global trial aims to boost survival for stomach cancer with new drug combo

NCT ID NCT04592913

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether adding an immunotherapy drug (durvalumab) to standard chemotherapy, given both before and after surgery, can help patients with operable stomach or gastroesophageal junction cancer live longer without their cancer returning. It compares the new combination against standard chemotherapy alone. The goal is to see if this approach better controls the disease and improves survival outcomes.

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Contacts and locations

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Locations

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Duarte, California, 91010, United States
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Los Angeles, California, 90027, United States
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Los Angeles, California, 90095, United States
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Sylmar, California, 91342, United States
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St. Petersburg, Florida, 33705, United States
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Tallahassee, Florida, 32308, United States
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West Palm Beach, Florida, 33401, United States
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Fort Wayne, Indiana, 46804, United States
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Louisville, Kentucky, 40217, United States
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Boston, Massachusetts, 02215, United States
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New York, New York, 10065, United States
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Rochester, New York, 14642, United States
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Nashville, Tennessee, 37203, United States
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Dallas, Texas, 75390, United States
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Lancaster, Texas, 75216, United States
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Seattle, Washington, 98109, United States
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Buenos Aires, C1431FWO, Argentina
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Ciudad Autonoma Buenos Aires, 1093, Argentina
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Ciudad de Buenos Aires, 1280, Argentina
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Ciudad de Buenos Aires, C1426ANZ, Argentina
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Rosario, 3101, Argentina
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Rosario, S2000DEJ, Argentina
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Charleroi, 6060, Belgium
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Edegem, 2650, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Roeselare, 8800, Belgium
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Barretos, 14784-400, Brazil
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Natal, 59075-740, Brazil
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Porto Alegre, 90035-903, Brazil
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Porto Alegre, 91350-200, Brazil
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Rio de Janeiro, 20231-050, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 01246-000, Brazil
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Edmonton, Alberta, t6G1Z2, Canada
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North York, Ontario, M2K 1E1, Canada
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Oshawa, Ontario, L1G 2B9,, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Montreal, Quebec, H2X 0A9, Canada
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Montreal, H3T 1E2, Canada
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La Serena, 1720430, Chile
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Santiago, 7500653, Chile
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Santiago, 7500921, Chile
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Talca, 3461341, Chile
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Temuco, 4800827, Chile
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Temuco, 4810218, Chile
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Aalborg, 9000, Denmark
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København Ø, 2100, Denmark
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Odense, 5000, Denmark
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Avignon, 84918, France
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Besançon, 25030, France
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Brest, 29609, France
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Dijon, 21000, France
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Lyon, 69373, France
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Montpellier, 34298, France
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Nantes, 44093, France
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Nice, 06100, France
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Paris, 75012, France
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Paris, 75475, France
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Paris, 75900, France
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Rennes, 35033, France
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Berlin, 13353, Germany
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Dresden, 01307, Germany
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Frankfurt, 60488, Germany
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Hamburg, 20246, Germany
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Hamburg, 20249, Germany
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Heidelberg, 69120, Germany
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Heilbronn, 74078, Germany
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Jena, 7743, Germany
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Mainz Am Rhein, 55131, Germany
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München, 81675, Germany
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Schweinfurt, 97421, Germany
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Tübingen, 72016, Germany
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Budapest, 1122, Hungary
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Győr, 9024, Hungary
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Kecskemét, 6000, Hungary
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Szekszárd, 7100, Hungary
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Szolnok, 5004, Hungary
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Chūōku, 104-0045, Japan
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Hidaka-shi, 350-1298, Japan
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Hirakata-shi, 573-1191, Japan
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Hiroshima, 730-8518, Japan
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Kashiwa, 277-8577, Japan
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Kitaadachi-gun, 362-0806, Japan
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Kochi, 781-8555, Japan
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Kurume-shi, 830-0011, Japan
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Nagoya, 464-8681, Japan
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Niigata, 951-8566, Japan
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Ogaki-shi, 503-8502, Japan
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Osaka, 534-0021, Japan
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Osaka, 541-8567, Japan
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Suita-shi, 565-0871, Japan
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Sunto-gun, 411-8777, Japan
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Tokyo, 135-8550, Japan
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Toyoake-shi, 470-1192, Japan
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Wakayama, 641-8510, Japan
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Yokohama, 241-8515, Japan
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Amsterdam, 1066 CX, Netherlands
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Eindhoven, 5623EJ, Netherlands
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Rotterdam, 3015GD, Netherlands
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Bellavista, CALLAO 2, Peru
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Lima, LIMA 29, Peru
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Lima, Lima 32, Peru
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Lima, LIMA 34, Peru
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San Isidro, 27, Peru
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Bialystok, 15-027, Poland
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Gdansk, 80-952, Poland
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Krakow, 30-688, Poland
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Lodz, 93-513, Poland
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Poznan, 60-569, Poland
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Poznan, 61-866, Poland
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Warsaw, 02-034, Poland
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Warsaw, 04-141, Poland
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Kaluga, 248007, Russia
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Moscow, 111123, Russia
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Moscow, 115478, Russia
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Moscow, 125284, Russia
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Novosibirsk, 630108, Russia
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Obninsk, 249036, Russia
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Saint Petersburg, 197089, Russia
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Hwasun-gun, 58128, South Korea
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Seongnam-si, 13620, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Barcelona, 08025, Spain
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Barcelona, 08035, Spain
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Barcelona, 08908, Spain
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Madrid, 28007, Spain
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Madrid, 28034, Spain
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Málaga, 29009, Spain
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Ourense, 32005, Spain
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Santander, 39008, Spain
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Seville, 41013, Spain
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Valencia, 46010, Spain
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Kaohsiung City, 807, Taiwan
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Taichung, 40443, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 10048, Taiwan
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Taipei, 112, Taiwan
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Taoyuan, 333, Taiwan
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Adana, 01120, Turkey (Türkiye)
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Ankara, 06340, Turkey (Türkiye)
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Erzurum, 25240, Turkey (Türkiye)
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Istanbul, 34098, Turkey (Türkiye)
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Istanbul, 34457, Turkey (Türkiye)
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Samsun, 55139, Turkey (Türkiye)
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Cambridge, CB2 0QQ, United Kingdom
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Dundee, DD1 9SY, United Kingdom
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Glasgow, G12 0YN, United Kingdom
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Leicester, LE2 7LZ, United Kingdom
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London, EC1A 7BE, United Kingdom
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Manchester, M20 4BX, United Kingdom
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Oxford, OX3 7LE, United Kingdom
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Surrey, SM2 5PT, United Kingdom

Conditions

Explore the condition pages connected to this study.

ESOPHAGOGASTRIC JUNCTION GASTROINTESTINAL NEOPLASMS