Mass STI treatment or daily pill? kenya trial tests best way to stop infections
NCT ID NCT06468462
First seen Nov 19, 2025 · Last updated Jun 19, 2026 · Updated 33 times
Summary
This study tests two approaches to prevent sexually transmitted infections (STIs) in cisgender men who have sex with men in Kenya. One group gets a single dose of antibiotics every few months, while another takes doxycycline after sex. The trial will track infections and antibiotic resistance over 18 months to see which strategy works better.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anza Mapema Clinic
RECRUITINGKisumu, Kenya
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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TRANSFORM Clinic
RECRUITINGNairobi, Kenya
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington/Pwani Research Centre at the Ganjoni Municipal Clinic, Mombasa
RECRUITINGMombasa, Kenya
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cefixime, azithromycin, and doxycycline
What this could lead to
If successful, this could provide effective strategies to control gonorrhea, chlamydia, and syphilis in high-risk populations in resource-limited settings.
What could go wrong
This is a Phase 4 trial, but results may not apply to other populations or settings. Antibiotic resistance is a concern, and the interventions may not reduce infections as hoped.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.