Could a meningitis shot also stop gonorrhea?
NCT ID NCT05294588
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a vaccine already approved for meningitis B (Bexsero) can also protect against gonorrhea infection. Healthy men aged 18–35 received either the meningitis vaccine or a placebo, then were exposed to the gonorrhea bacteria in a controlled setting. The goal was to see if the vaccine reduced infection rates. Results could help develop a new gonorrhea vaccine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 4C-MenB (Bexsero) vaccine
- What this could lead to
- If it works, this could point toward a vaccine that protects against gonorrhea, a common sexually transmitted infection.
- What could go wrong
- This is a small, early-phase trial in healthy men only. The vaccine is designed for meningitis, not gonorrhea, so it may not provide strong protection. Results may not apply to women or other populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Clinical and Translational Research Center (CTRC) at University of North Carolina (UNC) Hospitals and/or at UNC Global Clinical Research North
Chapel Hill, North Carolina, 27599-7215, United States
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