Simple shot vs. guided shot: which works better for carpal tunnel?
NCT ID NCT06725420
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to give steroid injections for mild-to-moderate carpal tunnel syndrome: one guided by ultrasound into the wrist, and one into the buttock muscle. 63 adults with symptoms like numbness and pain were followed to see which method improved pain, hand function, and strength better. The goal is to find a simpler, effective first-line treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- steroid injection
- What this could lead to
- If successful, this could show that a simpler intramuscular injection works as well as a guided local injection for carpal tunnel syndrome, offering a more accessible treatment option.
- What could go wrong
- This is a small, completed study with 63 participants, so results may not apply to everyone. Possible side effects include nerve injury, bleeding, infection, or temporary pain flare.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
63 people
The number who actually took part.
- Started
-
Dec 2024
- Finished
-
Oct 2025
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Presence of typical CTS symptoms (numbness, tingling, paresthesias, or pain that may be provoked by nighttime or activity-related posture * VAS score of ≥ 3/10 * Symptom duration longer than 12 weeks * Positive Tinel's and/or Phalen's sign * Electrophysiologically mild or moderate CTS being diagnosed. * Volunteer to participate in study Exclusion Criteria: * Patients with shoulder, elbow, wrist, or finger problems (e.g., impingement syndrome, epicondylitis, history of fractures in the wrist, de Quervain's tenosynovitis, trigger finger, Complex Regional Pain Syndrome (CRPS), Dupuytren's contracture). * Patients with a history of trauma or surgery in the affected hand, or those with significant anatomical deformities. * Patients with systemic diseases such as rheumatological disorders, hypothyroidism, amyloidosis, diabetes, gout, or chronic kidney failure. * Patients with conditions that may mimic CTS, such as polyneuropathy, plexopathy, cervical radiculopathy, or thoracic outlet syndrome. * Patients with cognitive dysfunction or communication issues. * Patients with severe CTS, neurological deficits (e.g., thenar atrophy, muscle weakness in thumb abduction/opposition), or those requiring surgical intervention. * Patients who have received local steroid injections or physical therapy to the hand/wrist within the last 6 months. * Patients who are receiving or will receive another/additional treatment for CTS. * Pregnant or lactating women. * Patients with active malignancies or local/systemic infections. * Patients who are receiving any active treatment (e.g., NSAIDs, oral/intramuscular steroids, acupuncture, other pain medications). * Patients with upper extremity involvement due to first motor neuron damage (e.g., stroke-hemiplegia, tetraparesis, multiple sclerosis). * Patients with a bifid median nerve, persistent median artery, ganglion cyst, tenosynovitis, or tendinitis in the wrist. * Use of a wrist splint during the last 6 months. * Allergy to corticosteroids or local anesthetics, and blood diathesis
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Carpal tunnel syndrome (CTS) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Konya Beyhekim Training and Research Hospital
Konya, 42060, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can carpal tunnel surgery restore more than hand function?
- Physical therapy may unlock lasting activity for older adults with joint pain
- Does nerve healing keep pace with hand recovery after carpal tunnel surgery?
- Can mindfulness ease chronic pain in the elderly?
- A phone app and a counselor take on the twin troubles of rural pain and drinking
- Could cannabis replace opioids for chronic pain?