Cooling the heart during a heart attack: a trial that never got started

NCT ID NCT03361995

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study planned to test whether cooling the body before and after opening a blocked artery could help people having a heart attack. It was designed to include 80 patients at up to 15 hospitals. However, the trial was withdrawn before anyone was enrolled, so we have no information on whether cooling is helpful or safe.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Cooling procedure using the ZOLL Thermogard XP3 IVTM System
What this could lead to
If it had worked, cooling might have reduced heart damage during a heart attack, potentially improving recovery.
What could go wrong
The trial was withdrawn before any patients were enrolled, so we have no data on whether cooling is safe or effective. Cooling also carries risks like shivering, infection, or heart rhythm problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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