Half-Matched stem cell transplant offers hope for severe sickle cell disease

NCT ID NCT03077542

First seen Apr 29, 2026 · Last updated May 12, 2026 · Updated 3 times

Summary

This study tests a new stem cell transplant method for adults with severe sickle cell disease. Participants receive stem cells from a half-matched relative after low-dose radiation and immune-suppressing drugs. The goal is to see if the transplant can control the disease without causing severe side effects like graft-versus-host disease.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.