Could a stem cell transplant tame severe immune disorders?

NCT ID NCT07284641

First seen Jan 09, 2026 · Last updated May 15, 2026 · Updated 16 times

Summary

This study tests a stem cell transplant for people aged 5 to 40 with severe immune disorders like common variable immunodeficiency (CVID) or other conditions that cause the immune system to attack the body. The goal is to replace the faulty immune system with a healthy donor's stem cells using a gentle chemotherapy and radiation approach. Researchers will track survival and how well the donor cells take over over time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for IMMUNE DYSREGULATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.