Stem cell shot aims to tame rheumatoid arthritis

NCT ID NCT04971980

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests a single intravenous infusion of stem cells from donated umbilical cords (BC-U001) in 9 adults with moderate-to-severe rheumatoid arthritis who haven't responded well to standard treatments. The main goal is to check safety and find the right dose, while also looking for signs of reduced joint inflammation and disease activity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

umbilical cord stem cells (BC-U001)

What this could lead to

If successful, this could point toward a new way to control rheumatoid arthritis with a single infusion, reducing inflammation and joint damage.

What could go wrong

This is a very early, small trial (9 people) focused on safety, not proof of effectiveness. The treatment may not work or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking Union Medical College Hospital (Dongdan campus)

    Beijing, Beijing Municipality, 100730, China