Stem cell shot for frailty? small study tests safety and promise

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age of 60-85 years old at the time of screening * Those who have been confirmed frailty indication through The Frail questionnaires * Those who voluntarily decided to participate in the study and wrote the informed consent form * Those who are suitable as subjects for this study when judged by physical examination, clinical test, medical test, et cetera Exclusion Criteria: * Subject that not able to perform any of the assessments required for endpoint analysis * Those who have hypersensitivity reaction or a history of hypersensitivity to the components of the investigational product or the investigational product * Subject with Mini Mental State Examination (MMSE) score less than 24 * Abnormal laboratory result, including Hemoglobin (Hb) \<8 g/dl, Leukocyte \<3000/mm3, platelets \<80,000/mm3, International Normalized Ratio (INR) \> 1.5, aspartate transaminase and alanine transaminase \> 3 times upper limit of normal, total bilirubin \> 1.5 mg/dl, serum creatinine \> 2 mg/dL * Organ transplant recipient or already listed (or expected to be listed) for transplantation of any organ * Patient taking immunosuppressive drugs within 6 months of screening * Having serious comorbidities that may compromise the safety and compliance of the patient based on investigator judgement, including but not limited to: 1) Heart: unstable angina, myocardial infarction, class III/IV congestive heart failure, cardiac revascularization within the last six months, 2) Liver: Advanced liver failure, 3) Renal: Advanced renal failure, 4) Pulmonary: Severe obstructive ventilatory defect, history of pulmonary embolism, 5) Other: Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS), Hepatitis B Surface Antigen (HBsAg) positive, Hepatitis C virus (HCV) positive, uncontrolled hypertension, uncontrolled blood glucose * Patient who had cancer disease within 5 years and no malignancy suspected from the result of tumor marker screening * Patient that participating in other investigational therapeutic or device trial * Patient with life expectancy less than 1 year * Patient who are pregnant, nursing, and/or having a childbearing potential while not having effective contraceptive method * Those who are determined by the investigator to be unsuitable for participation in the clinical trial due to other reasons including the results of the clinical laboratory test