Statins as gut microbiome modulators for ulcerative colitis: a failed promise?

NCT ID NCT04883840

First seen Nov 25, 2025 · Last updated May 01, 2026 · Updated 21 times

Summary

This study tested whether statins, a common cholesterol drug, could change gut bacteria to reduce inflammation in people with ulcerative colitis. It included 177 adults with mild to moderate disease. The study was terminated early, so results are limited, but the idea was to see if statins could shift gut bacteria toward a healthier profile and improve disease activity.

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Contacts and locations

Locations

  • AZ Delta

    Roeselare, West-Vlaanderen, 8800, Belgium

  • Imelda Ziekenhuis

    Bonheiden, Antwerp, 2820, Belgium

  • UZ Leuven

    Leuven, Vlaams-Brabant, 3000, Belgium

Conditions

Explore the condition pages connected to this study.