Genetic risk? this drug combo may stop heart plaque before it starts

NCT ID NCT05850091

First seen Mar 31, 2026 · Last updated May 13, 2026 · Updated 6 times

Summary

This study tests whether a high-intensity statin, low-dose colchicine, or both can slow or change the buildup of fatty plaque in the heart arteries. It includes 200 adults aged 40-75 who have a high genetic risk for heart disease but no symptoms yet. Participants will get one of the treatments or a placebo, and heart scans will measure plaque changes over one year.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.