New hope for rare nerve tumor pain: STARFISH trial launches

NCT ID NCT05684692

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests two experimental drugs (siltuximab and erenumab) to see if they can safely reduce chronic pain in people with schwannomatosis, a rare condition that causes painful nerve tumors. About 40 adults with moderate-to-severe pain will receive either the drug or a placebo for 12 weeks. The main goal is to measure changes in worst pain intensity using a standard 0–10 pain scale.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital Cancer Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.