New combo aims to shrink bladder tumors before surgery for cisplatin-ineligible patients

NCT ID NCT06394570

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 42 times

Summary

This study tests a combination of the drug enfortumab vedotin and targeted radiation before bladder removal surgery in people with muscle-invasive bladder cancer who cannot take the standard chemotherapy drug cisplatin. The goal is to see if this approach is safe and can eliminate or shrink the tumor before surgery. About 19 participants will receive different schedules of the drug and radiation to find the best dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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