New combo therapy aims to shrink bladder tumors before surgery

NCT ID NCT06394570

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 29 times

Summary

This study tests a combination of a targeted drug (enfortumab vedotin) and radiation therapy given before surgery for muscle-invasive bladder cancer. It is for patients who cannot receive standard chemotherapy with cisplatin. The goal is to see if this approach is safe and can eliminate or shrink the tumor before the bladder is removed. About 19 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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