Diabetes drug dapagliflozin tested to shield hearts during breast cancer treatment

NCT ID NCT07070765

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether dapagliflozin, a diabetes drug, can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. About 70 women aged 18-70 with low to medium heart risk will take either dapagliflozin or standard care during their chemo. The goal is to see if the drug helps keep the heart's energy levels healthy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dapagliflozin (a diabetes drug that may protect the heart)

What this could lead to

If it works, this could point toward a way to prevent heart damage in breast cancer patients receiving chemotherapy.

What could go wrong

This is a small, early-phase study (70 people) testing a drug not yet proven for this use. It may not show a clear benefit, and side effects from dapagliflozin are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cardiac Research Office, Aberdeen Royal Infirmary

    RECRUITING

    Aberdeen, Aberdeenshire, AB25 2ZD, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Aberdeen

    RECRUITING

    Aberdeen, AB25 2ZD, United Kingdom

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••