MRNA injection aims to turn back Skin's clock
NCT ID NCT06567119
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests a new injection called SPOT-mRNA01 in 10 healthy adults to see if it's safe and tolerable. The injection delivers mRNA that tells skin cells to make more collagen, which could reduce signs of aging. Participants receive a single shot under the skin, and researchers monitor side effects and measure collagen levels in the skin.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SPOT-mRNA01 (a messenger RNA that tells cells to produce collagen, delivered in tiny bubbles called extracellular vesicles)
- What this could lead to
- If it works, this could point toward a non-surgical treatment to reduce skin aging by boosting collagen.
- What could go wrong
- This is a very early Phase 1 trial with only 10 people, so it's mainly checking safety, not effectiveness. The approach is new and may not produce meaningful cosmetic results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SKIN AGING are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a mushroom compound turn back the clock on aging?
- Can different fillers turn back the clock on facial aging?
- Marine collagen: a daily sachet for youthful skin and stronger hair?
- Can a daily supplement turn back the clock on aging skin?
- Light and peel combo may turn back the clock on aging hands
- A skin biostimulator aims to reverse sun damage without the peel downtime