Could a common pill help prevent aortic rupture?

NCT ID NCT07483177

First seen Mar 20, 2026 · Last updated May 06, 2026 · Updated 7 times

Summary

This study tests whether spironolactone, a medication typically used for heart failure, can reduce stiffness in the main artery of patients with a thoracic aortic aneurysm. Fifty adults with an enlarged aorta will receive either spironolactone or a placebo for a short period. The goal is to see if the drug improves artery flexibility, which could help manage the condition and lower the risk of complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.