New MRI technique aims to spot hidden heart problems
NCT ID NCT06854458
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will enroll 1,000 adults aged 35-85 with chest pain or shortness of breath to see if a new, detailed MRI blood flow measurement can more accurately diagnose heart disease than standard MRI. Participants will receive a contrast agent called Gadavist during stress and rest imaging. The goal is to improve diagnosis and reduce unnecessary invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gadavist (gadobutrol contrast agent)
What this could lead to
If successful, this could make heart disease diagnosis more accurate and help doctors better understand its severity without invasive procedures.
What could go wrong
This is an observational study, not a treatment trial. The new MRI method may not prove more useful than standard imaging, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atrium Health - Sanger Heart & Vascular Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Francis Hospital and Heart Center
RECRUITINGRoslyn, New York, 11576, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco
RECRUITINGSan Francisco, California, 94107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22908, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UofL Health - Heart Hospital
RECRUITINGLouisville, Kentucky, 40202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37203, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23298, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact