Can a spinal injection safely slow spinal muscular atrophy? a real-world study in korea seeks answers.

NCT ID NCT04317794

Ongoing Disease control Sponsor: Biogen Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This study tracks the safety and effectiveness of Spinraza (nusinersen) in people with spinal muscular atrophy (SMA) who receive the drug as part of routine care in Korea. Researchers will monitor for side effects and measure changes in motor skills over time. The goal is to see how well the treatment works outside of controlled clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nusinersen (Spinraza), a drug injected into the spinal fluid to treat spinal muscular atrophy
What this could lead to: If successful, this study could confirm that Spinraza is safe and effective for SMA patients in real-world Korean clinics.
What could go wrong: This is an observational study, not a controlled trial, so results may be less definitive. Side effects like injection-site reactions or serious adverse events are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MUSCULAR ATROPHY, SPINAL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

spinal muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MUSCULAR ATROPHY, SPINAL

Contacts and locations

Locations

Asan Medical Center

Seoul, South Korea
Chonbuk National University Hospital

Jeonju, South Korea
Chonnam National University Hospital

Gwangju, South Korea
Chungbuk National University Hospital

Cheongju-si, South Korea
Chungnam National University Hospital

Daejeon, South Korea
Korea University Guro Hospital

Seoul, South Korea
Korea university Anam Hospital

Seoul, South Korea
Kyungpook National University Hospital

Daegu, South Korea
Pusan Natioanl University Hospital

Busan, South Korea
Pusan National University Yangsan Hospital

Yangsan, South Korea
Samsung Changwon Hospital

Changwon, South Korea
Samsung Medical Center

Seoul, South Korea
Seoul Natioanl University Hospital

Seoul, South Korea
Severance Hospital

Seoul, 03722, South Korea
Severance Hospital, Yonsei University Health System

Seoul, South Korea
Yeungnam University Hospital

Daegu, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.