New bone graft study aims to improve spine surgery outcomes

NCT ID NCT04073563

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a special bone graft (Infuse) helps spine bones fuse together better after back surgery. About 600 adults with degenerative spine disease will be followed for two years. The goal is to see if the graft reduces pain, improves function, and safely helps bones heal.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lumbar disk degenerative disorder lumbar disk disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advent Health Altamonte Springs

    Altamonte Springs, Florida, 32701, United States

  • Advent Health Orlando

    Orlando, Florida, 32803, United States

  • American Neurospine Institute

    Plano, Texas, 75075, United States

  • Baystate Medical Center

    Springfield, Massachusetts, 01199, United States

  • Boulder Neurosurgical Associates and Justin Parker Neurological Institute/E. Lee Nelson

    Boulder, Colorado, 80303, United States

  • Cedars Sinai Spine Center

    Los Angeles, California, 90048, United States

  • Chongqing Xinqiao Hospital Second Affiliated Hospital of Army Medical University

    Chongqing, 400000, China

  • DFW Center for Spinal Disorder

    Fort Worth, Texas, 76132, United States

  • Foundation for Orthopaedic Research and Education

    Tampa, Florida, 33637, United States

  • Goodman Campbell Brain and Spine

    Carmel, Indiana, 46032, United States

  • Hartford Hospital

    Hartford, Connecticut, 06106, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Indiana Spine Group

    Carmel, Indiana, 46032, United States

  • Lahey Hospital & Medical Center

    Burlington, Massachusetts, 01805, United States

  • Mayfield Brain and Spine Clinic

    Cincinnati, Ohio, 45209, United States

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    Rochester, Minnesota, 55901, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Health Services

    Laguna Hills, California, 92653, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Orlando Health

    Orlando, Florida, 32806, United States

  • OrthoIndy Northwest Office

    Indianapolis, Indiana, 46278, United States

  • Peking University Third Hospital

    Beijing, China

  • Penn State-Hershey

    Hershey, Pennsylvania, 17033, United States

  • Rothman Institute

    Philadelphia, Pennsylvania, 19107, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Saint Thomas for Specialty Surgery

    Nashville, Tennessee, 37203, United States

  • Semmes Murphey

    Memphis, Tennessee, 38120, United States

  • Swedish Neuroscience

    Seattle, Washington, 98122, United States

  • Tennessee Orthopaedic Alliance

    Nashville, Tennessee, 37209, United States

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • University of Arizona

    Tucson, Arizona, 85724, United States

  • University of California Davis Medical Center

    Sacramento, California, 95816, United States

  • University of California Irvine

    Irvine, California, 92617, United States

  • University of Colorado Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • University of Iowa Hospitals and Clinic

    Iowa City, Iowa, 52242, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of Virginia - Clinical Trial Office

    Charlottesville, Virginia, 22904, United States

  • University of Virginia - Health System

    Charlottesville, Virginia, 22908, United States

  • Vail-Summit Orthopaedics and Neurosurgery

    Vail, Colorado, 81657, United States

  • West China Hospital of Sichuan University

    Chengdu, China

  • West Virginia University, 1 Medical Center Drive

    Morgantown, West Virginia, 26506, United States

  • William Beaumont Hospital

    Royal Oak, Michigan, 48073, United States