New pill targets hormone imbalance from adrenal tumors

NCT ID NCT05436639

Completed Disease control Sponsor: Sparrow Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a daily pill called SPI-62 in 30 adults with high cortisol levels caused by a non-cancerous adrenal tumor. The goal was to see if the drug could safely lower blood sugar and improve other health measures. Participants took 2 mg of SPI-62 each day for up to 12 weeks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUTONOMOUS CORTISOL SECRETION (ACS) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ACTH-independent adrenal Cushing syndrome, somatic ACTH-independent Cushing syndrome Cushing syndrome due to macronodular adrenal hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTH-INDEPENDENT ADRENAL CUSHING SYNDROME, SOMATIC ACTH-INDEPENDENT CUSHING SYNDROME AUTONOMOUS CORTISOL SECRETION (ACS)

Contacts and locations

Show contact details

Locations

C.M.D.T.A. Neomed

Brasov, 500283, Romania
Institutul National de Endocrinologie

Bucharest, 11863, Romania
King's College Hospital

London, SW9 8RR, United Kingdom
Mayo Clinic Cancer Center (MCCC) - Rochester

Rochester, Minnesota, 55905, United States
Ohio State McCampbell Outpatient Care

Columbus, Ohio, 43210, United States