New drug shows promise for cortisol disorder
NCT ID NCT05307328
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an experimental drug called SPI-62 in 26 adults with Cushing's syndrome caused by a non-adrenal tumor. The goal was to see if SPI-62 could lower cortisol levels safely. Participants received either SPI-62 or a placebo for 24 weeks, with an option to continue longer.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Carol Davila University of Medicine and Pharmacy
Bucharest, 050474, Romania
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Clinical Center of Endocrinology and Gerontology, University Hospital of Endocrinology, Medical University Sofia (USHATE)
Sofia, 1431, Bulgaria
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Comprehensive and Interventional Pain Management Llp
Henderson, Nevada, 89052, United States
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Mayo Clinic Cancer Center (MCCC) - Rochester
Rochester, Minnesota, 55905, United States
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Medical University of Plovdiv
Plovdiv, 4002, Bulgaria
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Medical University of Sofia
Sofia, 1431, Bulgaria
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
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Oregon Health & Science University (OHSU) - Northwest Pituitary Center
Portland, Oregon, 97239, United States
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Southwest General Healthcare Center
Fort Myers, Florida, 33907, United States
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St. Joseph's Hospital and Medical Center - Barrow Neurological Institute (BNI) - Pituitary Center
Phoenix, Arizona, 85013, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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Washington University School of Medicine - Center for Advanced Medicine (CAM)
St Louis, Missouri, 63110, United States