New heart catheter aims to stop dangerous rhythms in their tracks

NCT ID NCT06703489

First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 36 times

Summary

This study is testing a new device called the Sphere-9 catheter, used with the Affera mapping system, to treat ventricular tachycardia (VT) — a fast, dangerous heart rhythm. The procedure uses heat to destroy small areas of scarred heart tissue that cause the abnormal rhythm. The trial will enroll 60 adults who have had repeated episodes of VT linked to heart scarring. Researchers will check if the procedure is safe and if it can stop VT from happening again.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Texas Cardiac Arrhythmia Research Foundation

    RECRUITING

    Austin, Texas, 78705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sphere-9 catheter and Affera ablation system (device)

What this could lead to

If successful, this could provide a new, more effective way to treat ventricular tachycardia by precisely destroying the heart tissue causing dangerous rhythms.

What could go wrong

This is an early feasibility study with only 60 participants, so results may not apply to everyone. There are risks of serious complications like heart or lung problems from the procedure.

Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac cardiovascular disorder heart disorder myocardial ischemia Pathologic Processes ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.