Balloon battle: could a Drug-Coated balloon replace stents in tiny heart vessels?

NCT ID NCT07397845

Recruiting now Disease control Sponsor: Translumina GmbH Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for narrowed small heart arteries: paclitaxel-coated balloons versus drug-eluting stents. About 1,380 people with stable or unstable chest pain will be randomly assigned to one of two balloon types or a standard stent. The goal is to see if balloons work as well as stents at preventing heart-related death, heart attacks, or the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paclitaxel-coated balloon catheter
What this could lead to: If successful, this could offer a stent-free option for treating small, complex heart arteries, potentially reducing long-term complications.
What could go wrong: This is an early-stage trial without a phase designation, so results are uncertain. Balloons may not keep arteries open as well as stents, and there is a risk of vessel closure or heart attack.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE DRUG ELUTING BALLOON DRUG-ELUTING STENT

Contacts and locations

Locations

Luzerner Kantonsspital Spitalstrasse, 6000 Luzern 16, Switzerland
RECRUITING

Lucerne, Canton of Lucerne, 6000 Luzern 16, Switzerland

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