Balloon battle: could a Drug-Coated balloon replace stents in tiny heart vessels?

NCT ID NCT07397845

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for narrowed small heart arteries: paclitaxel-coated balloons versus drug-eluting stents. About 1,380 people with stable or unstable chest pain will be randomly assigned to one of two balloon types or a standard stent. The goal is to see if balloons work as well as stents at preventing heart-related death, heart attacks, or the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon catheter

What this could lead to

If successful, this could offer a stent-free option for treating small, complex heart arteries, potentially reducing long-term complications.

What could go wrong

This is an early-stage trial without a phase designation, so results are uncertain. Balloons may not keep arteries open as well as stents, and there is a risk of vessel closure or heart attack.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Luzerner Kantonsspital Spitalstrasse, 6000 Luzern 16, Switzerland

    RECRUITING

    Lucerne, Canton of Lucerne, 6000 Luzern 16, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••