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New study maps the path from smoldering to active myeloma

NCT ID NCT06472778

Completed Knowledge-focused Sponsor: Janssen-Cilag Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study reviewed medical records of 431 people with smoldering multiple myeloma (SMM), a pre-cancerous condition, to see how the disease progresses over time. Researchers looked at which patients are at higher risk of developing active multiple myeloma and what treatments they received. The goal is to better predict and manage the transition from smoldering to active disease.

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Conditions

The condition(s) this trial relates to.

Smoldering Multiple Myeloma smoldering plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOLDERING MULTIPLE MYELOMA

Contacts and locations

Locations

  • Azienda Ospedaliera Universitaria Careggi

    Florence, 50134, Italy

  • Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino

    Torino, 10126, Italy

  • Azienda Ospedaliera Universitaria Policlinico Umberto I - Universita di Roma La Sapienza

    Roma, 00161, Italy

  • Barts Hospital

    London, EC1 7ED, United Kingdom

  • Birmingham Heartlands Hospital

    Birmingham, B9 5SS, United Kingdom

  • CH Rene Dubos

    Pontoise, 95303, France

  • CHRU de Tours - Hopital Trousseau

    Chambray-lès-Tours, 37170, France

  • CHU Montpellier

    Montpellier, 34295, France

  • Centre Hospitalier Regional d'Orleans (CHRO) - Hopital La Source

    Orléans, 45100, France

  • Churchill Hospital

    Oxford, OX3 7LE, United Kingdom

  • ELBLANDKLINIKUM Riesa

    Riesa, 1589, Germany

  • Hopital Pitie Salpetriere

    Paris, 75013, France

  • Hosp Clinico Univ de Salamanca

    Salamanca, 37007, Spain

  • Hosp Univ A Coruna

    A Coruña, 15006, Spain

  • Hosp. Clinico Univ. de Valladolid

    Valladolid, 47003, Spain

  • Hosp. Prov. de Avila

    Ávila, 05004, Spain

  • Hosp. San Pedro de Alcantara

    Cáceres, 10003, Spain

  • Hosp. Univ. Lucus Augusti

    Lugo, 27003, Spain

  • Hosp. Univ. de Alava

    Vitoria-Gasteiz, 01005, Spain

  • Kent and Canterbury Hospital

    Canterbury, CT1 3NG, United Kingdom

  • Manchester Royal Infirmary

    Manchester, M13 9WL, United Kingdom

  • Ospedale San Raffaele

    Milan, 20132, Italy

  • Policlinico Universitario Agostino Gemelli

    Roma, 00168, Italy

  • South Tees Hospitals NHS Foundation Trust

    North Yorks, TS4 3BY, United Kingdom

  • Studienzentrum Gefos Dortmund mbH

    Dortmund, 44263, Germany

  • Universitaetsklinikum Hamburg Eppendorf

    Hamburg, 20246, Germany

  • Universitaetsklinikum Tuebingen

    Tübingen, 72076, Germany

  • University Hospital of Wales

    Cardiff, CF14 4XW, United Kingdom

  • University Hospitals Of Leicester Nhs Trust

    Leicester, LE1 5WW, United Kingdom

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