Ear gel may shield cancer patients from Chemo-Induced deafness

NCT ID NCT07281508

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a special gel (sodium thiosulfate) into the ear before each round of cisplatin chemotherapy can prevent hearing loss. About 100 adults with head and neck cancer will receive the gel in one ear only, so the treated ear can be compared to the untreated ear. The goal is to see if the gel protects hearing without affecting the cancer treatment.

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Conditions

The condition(s) this trial relates to.

head and neck cancer platinum-induced ototoxicity prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Antoni van Leeuwenhoek

    RECRUITING

    Amsterdam, North Holland, 1066CX, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Erasmus Universitair Medisch Centrum Rotterdam

    NOT_YET_RECRUITING

    Rotterdam, South Holland, 3015GD, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Leiden University Medical Center

    RECRUITING

    Leiden, South Holland, 2333ZA, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stichting Radboud University Medical Center

    NOT_YET_RECRUITING

    Nijmegen, 6525GA, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Medical Center Utrecht

    NOT_YET_RECRUITING

    Utrecht, Utrecht, 3584CX, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact