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New drug tested to help japanese patients breathe easier with serious lung disease

NCT ID NCT05818137

Completed Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding a new drug called Sotatercept to existing treatments could help Japanese adults with pulmonary arterial hypertension (PAH), a serious condition where high blood pressure damages the lungs and heart. The 46 participants received Sotatercept injections for 24 weeks while continuing their standard PAH medications. Researchers measured changes in lung blood pressure, walking ability, and heart strain to see if the add-on treatment improved their condition.

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Contacts and locations

Locations

  • Chiba Saiseikai Narashino hospital ( Site 2004)

    Narashino, Chiba, 275-8580, Japan

  • Chiba University Hospital ( Site 2003)

    Chiba, 260-8677, Japan

  • Hamamatsu University Hospital ( Site 2016)

    Hamamatsu, Shizuoka, 431-3192, Japan

  • Hokkaido University Hospital ( Site 2001)

    Sapporo, Hokkaido, 060-8648, Japan

  • International University of Health and Welfare Mita Hospital ( Site 2008)

    Tokyo, 108-8329, Japan

  • Keio university hospital ( Site 2007)

    Tokyo, 1608582, Japan

  • Kobe University Hospital ( Site 2012)

    Kobe, Hyōgo, 650-0017, Japan

  • Kure Kyosai Hospital ( Site 2017)

    Kure, Hiroshima, 7378505, Japan

  • Kurume University Hospital ( Site 2014)

    Kurume, Fukuoka, 830-0011, Japan

  • Kyorin University Hospital ( Site 2005)

    Mitaka, Tokyo, 181-8611, Japan

  • Kyushu University Hospital ( Site 2015)

    Fukuoka, 812-8582, Japan

  • Nagoya University Hospital ( Site 2010)

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Cerebral and Cardiovascular Center ( Site 2011)

    Suita, Osaka, 564-8565, Japan

  • National Hospital Organization Okayama Medical Center ( Site 2013)

    Okayama, 701-1192, Japan

  • Sapporo Medical University Hospital ( Site 2018)

    Sapporo, Hokkaido, 060-8543, Japan

  • The University of Tokyo Hospital ( Site 2006)

    Bunkyo-ku, Tokyo, 113-8654, Japan

  • Tohoku University Hospital ( Site 2002)

    Sendai, Miyagi, 980-8574, Japan

Conditions

Explore the condition pages connected to this study.

PULMONARY ARTERIAL HYPERTENSION