PAH drug safety tested in extension study

NCT ID NCT06925750

Ongoing Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This study continues testing sotatercept, an investigational medicine for pulmonary arterial hypertension (PAH), to check its long-term safety when given in weight-based doses. It's open only to people who completed a previous trial of this drug and haven't started commercial treatment. The main goal is to see how well people tolerate the medicine over a longer period and track any side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

AOU Policlinico Umberto I ( Site 0910)

Roma, 00161, Italy
Asan Medical Center ( Site 1303)

Seoul, 05505, South Korea
Azienda Ospedaliera Universitaria Integrata ( Site 0908)

Verona, Veneto, 37126, Italy
C.H.U Hôpital Nord ( Site 0500)

Marseille, Bouches-du-Rhone, 13015, France
CHU Bordeaux Haut-Leveque ( Site 0501)

Pessac, Aquitaine, 33600, France
CHU GABRIEL MONTPIED ( Site 0504)

Clermont-Ferrand, Puy-de-Dome, 63000, France
CHU de Rouen ( Site 0503)

Rouen, Haute-Normandie, 76000, France
Carmel Hospital ( Site 0803)

Haifa, 3436212, Israel
Centro Medico Capital ( Site 0002)

La Plata, Buenos Aires, B1904AAW, Argentina
Chonnam National University Hospital ( Site 1304)

Gwangju, Kwangju-Kwangyokshi, 61469, South Korea
Clinica Colsanitas - Sede Reina Sofia ( Site 0303)

Bogotá, Bogota D.C., 110111, Colombia
Clínica Imbanaco S.A.S ( Site 0304)

Cali, Valle del Cauca Department, 760042, Colombia
Faculty of Medicine Siriraj Hospital ( Site 1600)

Bangkoknoi, Bangkok, 10700, Thailand
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico ( Site 0902)

Milan, Lombardy, 20122, Italy
Fondazione IRCCS Policlinico San Matteo ( Site 0909)

Pavia, 27100, Italy
Fundacion Santa Fe de Bogota ( Site 0302)

Bogotá, Bogota D.C., 110111, Colombia
Golden Jubilee National Hospital ( Site 1800)

Glasgow, Scotland, G81 4DY, United Kingdom
Gottsegen György Országos Kardiovaszkuláris Intézet ( Site 0702)

Budapest, Pest County, 1096, Hungary
Guangdong Provincial People's Hospital-Cardiology ( Site 2000)

Guangzhou, Guangdong, 510080, China
HOSPITAL GENERAL UNIVERSITARIO DE TOLEDO ( Site 1408)

Toledo, 45007, Spain
Hammersmith Hospital ( Site 1801)

London, London, City of, W12 OHS, United Kingdom
Hospital Clinic de Barcelona ( Site 1406)

Barcelona, Catalonia, 08036, Spain
Hospital Provincial Jose Maria Cullen ( Site 0005)

Santa Fe, S3000EOM, Argentina
Hospital Universitari Son Espases ( Site 1412)

Palma, Balearic Islands, 07120, Spain
Hospital Universitari Vall d''Hebron ( Site 1404)

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre ( Site 1403)

Madrid, 28041, Spain
Hospital Universitario La Paz ( Site 1410)

Madrid, 28046, Spain
Hospital Universitario Marqués de Valdecilla ( Site 1405)

Santander, Cantabria, 39008, Spain
Hospital Universitario Virgen del Rocio ( Site 1407)

Seville, 41013, Spain
IMAT S.A.S ( Site 0301)

Montería, Departamento de Córdoba, 230002, Colombia
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 0905)

Bologna, 40139, Italy
IUCPQ ( Site 0208)

Québec, Quebec, G1V 4G5, Canada
Instituto Medico Rio Cuarto ( Site 0010)

Río Cuarto, Córdoba Province, X5800AEV, Argentina
Instituto de Cardiologia Juana F. Cabral ( Site 0008)

Corrientes, W3400AMZ, Argentina
Instituto de Investigaciones Clinicas Mar del Plata ( Site 0006)

Mar del Plata, Buenos Aires, B7600FZO, Argentina
Kyorin University Hospital ( Site 2100)

Mitaka, Tokyo, 181-8611, Japan
Kyushu University Hospital ( Site 2105)

Fukuoka, 812-8582, Japan
Maharaj Nakorn Chiang Mai Hospital ( Site 1601)

Muang, Chiang Mai, 50200, Thailand
Nagoya University Hospital ( Site 2102)

Nagoya, Aichi-ken, 466-8560, Japan
National Cerebral and Cardiovascular Center ( Site 2103)

Suita, Osaka, 564-8565, Japan
National Cheng Kung University Hospital ( Site 1501)

Tainan, 704302, Taiwan
National Heart Centre Singapore ( Site 1201)

Singapore, Central Singapore, 169609, Singapore
National Hospital Organization Okayama Medical Center ( Site 2104)

Okayama, 701-1192, Japan
National University Heart Centre, Singapore ( Site 1200)

Singapore, Central Singapore, 119074, Singapore
Ospedale Civile SS Annunziata ( Site 0903)

Sassari, 07100, Italy
Ospedale San Martino ( Site 0901)

Genova, 16132, Italy
Pusan National University Hospital ( Site 1305)

Seogu, Pusan-Kwangyokshi, 49241, South Korea
Rabin Medical Center ( Site 0805)

Petah Tikva, 4941492, Israel
Radboud University Medical Center ( Site 1001)

Nijmegen, Gelderland, 6525 GA, Netherlands
Rambam Health Care Campus ( Site 0802)

Haifa, 3109601, Israel
Royal Brompton Hospital ( Site 1804)

London, London, City of, SW3 6HP, United Kingdom
Royal Free Hospital ( Site 1803)

London, England, NW3 2QG, United Kingdom
Royal Papworth Hospital ( Site 1802)

Cambridge, Cambridgeshire, CB2 0AY, United Kingdom
Royal Prince Alfred Hospital ( Site 0103)

Camperdown, New South Wales, 2050, Australia
Samsung Medical Center ( Site 1301)

Seoul, 06351, South Korea
Semmelweis Egyetem ( Site 0701)

Budapest, Pest County, 1083, Hungary
Seoul National University Hospital ( Site 1302)

Seoul, 03080, South Korea
Severance Hospital Yonsei University Health System ( Site 1300)

Seoul, 03722, South Korea
Shanghai Pulmonary Hospital ( Site 2004)

Shanghai, Shanghai Municipality, 200433, China
Sheba Medical Center ( Site 0801)

Ramat Gan, 5265601, Israel
Sint Antonius Ziekenhuis ( Site 1000)

Nieuwegein, Utrecht, 3435CM, Netherlands
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Családorvosi Intézet és Rendelő ( Site 0704)

Szeged, Csongrád megye, 6725, Hungary
Taipei Veterans General Hospital ( Site 1502)

Taipei, 112201, Taiwan
The Alfred Hospital ( Site 0102)

Melbourne, Victoria, 3004, Australia
The Second Xiangya Hospital of Central South University ( Site 2002)

Changsha, Hunan, 410011, China
The University of Tokyo Hospital ( Site 2101)

Bunkyo, Tokyo, 113-8655, Japan
University of Colorado Anschutz Medical Campus-University of Colorado Hospital Cardiac and Vascular ( Site 1930)

Aurora, Colorado, 80045, United States
University of Kansas Medical Center ( Site 1928)

Kansas City, Kansas, 66160, United States
University of New Mexico Health Sciences Center - Department of Internal Medicine ( Site 1916)

Albuquerque, New Mexico, 87131, United States
Vseobecna fakultni nemocnice v Praze ( Site 0400)

Prague, Praha 2, 128 08, Czechia
Wesley Research Institute ( Site 0101)

Auchenflower, Queensland, 4066, Australia
Westmead Hospital ( Site 0100)

Westmead, New South Wales, 2145, Australia
Yan an Hospital of Kunming City ( Site 2011)

Kunming, Yunnan, 650051, China

Conditions

Explore the condition pages connected to this study.

PULMONARY ARTERIAL HYPERTENSION