New study tracks sorafenib safety in Hard-to-Treat thyroid cancer

NCT ID NCT02185560

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study monitors 453 patients with advanced thyroid cancer that cannot be removed by surgery and does not respond to radioactive iodine. All patients are taking the drug sorafenib (Nexavar) as part of their normal care. Researchers are tracking side effects and how long patients live or stay on treatment over 9 to 24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sorafenib (Nexavar)

What this could lead to

If successful, this study will confirm the safety and real-world effectiveness of sorafenib for advanced thyroid cancer, supporting its continued use.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may be limited by short follow-up and lack of a comparison group.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

differentiated thyroid carcinoma thyroid gland carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study site

    Multiple Locations, Japan