Sound waves may wake up immune system against liver tumors

NCT ID NCT07365527

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using ultrasound with a contrast agent (sonoporation) can change the environment inside liver tumors that have spread from colorectal cancer. 48 adults will be randomly assigned to receive either low- or high-intensity ultrasound, or no ultrasound. The goal is to see if this procedure can make the tumor more welcoming to immune cells, potentially boosting future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
contrast-enhanced ultrasound (SonoVue)
What this could lead to
If it works, this could point toward a way to make liver tumors more responsive to the body's own immune system.
What could go wrong
This is a very early, small study (48 people) testing safety and biological effects, not treatment success. It may not lead to any direct benefit for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LIVER METASTASES FROM COLORECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

  • Surgical Department, Zealand University Hospital

    RECRUITING

    Køge, 4600, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.