Could this pill beat long COVID fatigue?
NCT ID NCT07298005
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests whether the drug sonlicromanol can reduce fatigue in 80 people with long COVID who experience post-exertional malaise (worsening symptoms after activity). Participants take the drug or a placebo twice daily for 13 weeks, and researchers measure changes in fatigue, muscle strength, and thinking ability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sonlicromanol
What this could lead to
If it works, this could point toward a treatment for severe fatigue in people with long COVID.
What could go wrong
This is a small, early-phase trial with only 80 participants. The drug may not reduce fatigue better than a placebo, and it is not a cure.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amsterdam University Medical Center, Location Academic Medical Center (AMC)
RECRUITINGAmsterdam, North Holland, 1105 AZ, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••