A blood clue to a rare vessel disease?

NCT ID NCT03698071

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This study looks at whether a protein in the blood, called soluble CD95 ligand, plays a role in ANCA-associated vasculitis, a rare group of diseases that cause inflammation of blood vessels. Researchers will collect blood and urine samples from 48 adults with the condition and track changes in the protein's levels over 12 months. The goal is to see if this marker could help with diagnosis, predicting disease activity, or finding new treatment approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Blood and urine sample collection for biomarker analysis
What this could lead to
If the marker proves reliable, it could lead to a simple blood test to help diagnose or monitor ANCA-associated vasculitis, and possibly point toward new treatments.
What could go wrong
This is an observational study with a small number of participants, so the marker may not prove accurate or broadly applicable. It is exploratory and does not test any treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Bordeaux - Service d'Immunologie et Immunogénétique

    Bordeaux, France

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