Virus therapy targets superbug in transplant patients

NCT ID NCT06938867

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new treatment called SNIPR001, which uses specially designed viruses to kill a type of antibiotic-resistant E. coli bacteria. The trial includes 24 adults with blood cancer who are scheduled for a stem cell transplant and already carry these resistant bacteria. Participants will receive either SNIPR001 or a placebo alongside standard antibiotics to see if it is safe and can reduce the bacteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SNIPR001 (a mixture of viruses that target E. coli bacteria)

What this could lead to

If it works, this could help prevent dangerous E. coli infections in stem cell transplant patients who carry resistant bacteria.

What could go wrong

This is a very early, small trial with only 24 participants. The treatment may not work or could cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

escherichia coli infection hematopoietic and lymphoid cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • John Hopkins University

    RECRUITING

    Baltimore, Maryland, 21218, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC

    RECRUITING

    Pittsburgh, Pennsylvania, 15213-2582, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94118, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••