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Nose ointment may ease Radiation's brutal mouth pain

NCT ID NCT07524894

Not yet recruiting Symptom relief Sponsor: David Palma Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a common antibiotic ointment applied inside the nose can reduce severe mouth and throat pain caused by radiation therapy in head and neck cancer patients. About 126 participants will receive either the antibiotic or a placebo, and neither they nor their doctors will know which. The goal is to see if clearing a common nasal bacteria (Staph) can prevent worsening of radiation-induced mouth sores and pain.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma mucositis staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER RADIATION MUCOSITIS STAPHYLOCOCCAL AUREUS INFECTION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • London Health Sciences Centre

    London, Ontario, N6A5W9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••