Can Low-Nicotine cigarettes help smokers in opioid treatment?

NCT ID NCT06747871

First seen Jan 11, 2026 · Last updated Jun 10, 2026 · Updated 24 times

Summary

This study looks at whether switching to very low nicotine cigarettes affects cravings, withdrawal, and pain in daily smokers who have chronic pain and are on buprenorphine treatment for opioid use disorder. About 60 adults will be assigned to either low-nicotine or regular-nicotine cigarettes for several weeks. Researchers will track smoking habits, pain levels, and withdrawal symptoms to understand how nicotine reduction might help this group.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • North Pavilion

    RECRUITING

    Durham, North Carolina, 27705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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