Could spinal cord stimulation help repair nerves in small fiber neuropathy?
NCT ID NCT07704931
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This pilot study looks at whether spinal cord stimulation can improve nerve health in people with small fiber neuropathy, a condition that causes chronic pain. Researchers will measure changes in nerve fiber density from skin biopsies taken before and after 12 months of routine clinical care with the Evoke spinal cord stimulation system. The study does not assign or change treatment—it simply observes outcomes in up to 10 adults already receiving this therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ECAP-controlled spinal cord stimulation using the Saluda Evoke system
- What this could lead to
- If it shows that spinal cord stimulation can improve nerve fiber density, this could point toward a new way to treat small fiber neuropathy.
- What could go wrong
- This is a very small pilot study with only 10 people, so results may not apply to everyone. It is observational, so it cannot prove cause and effect.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Grand Island Pain Relief Center
Grand Island, Nebraska, 68803, United States
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