Broken sleep could make painkillers more addictive, study finds

NCT ID NCT04299490

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 22 times

Summary

This study looked at how disrupted sleep changes the way painkillers work in the brain and whether it makes them more addictive. Healthy adults aged 18-48 with normal sleep patterns took part in experiments where their sleep was purposely broken up. Researchers measured pain relief, brain activity, and drug abuse risk to understand the connection between poor sleep and pain medication.

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Contacts and locations

Locations

  • Johns Hopkins School of Medicine

    Baltimore, Maryland, 21224, United States

Conditions

Explore the condition pages connected to this study.