New drug aims to prevent breathing problems after surgery for sleep apnea patients

NCT ID NCT05814016

Summary

This study tested whether a single dose of an experimental drug called danavorexton could help people with moderate to severe sleep apnea breathe more easily in the recovery room after abdominal surgery. The trial involved about 41 participants who were randomly assigned to receive either the drug at different doses or a placebo. The main goal was to see if the drug could help patients maintain stable breathing for two hours after waking from anesthesia.

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Contacts and locations

Locations

  • Brigham and Womens Hospital

    Boston, Massachusetts, 02115-6110, United States

  • Cedars Sinai Medical Hospital

    West Hollywood, California, 90048, United States

  • Cleveland Clinic Florida

    Weston, Florida, 33331-3609, United States

  • Cleveland Clinic Hospital

    Cleveland, Ohio, 44195-0001, United States

  • Fairview Hospital

    Cleveland, Ohio, 44111-5612, United States

  • Helen Keller Hospital

    Sheffield, Alabama, 35660-6334, United States

  • Inspira Health

    Mullica Hill, New Jersey, 09061, United States

  • Mayo Clinic - PPDS - Hospital

    Phoenix, Arizona, 85054-4502, United States

  • Mayo Clinic Jacksonville - PPDS

    Jacksonville, Florida, 32224-1865, United States

  • Medical Research Center - Clinic/Outpatient Facility

    Miami, Florida, 33165, United States

  • NYU Langone

    Mineola, New York, 11501-3893, United States

  • Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210-1240, United States

  • Rush University

    Chicago, Illinois, 60622, United States

  • Stony Brook University Medical Center

    Stony Brook, New York, 11794-0001, United States

  • The Medical College of Wisconsin, Inc.

    Milwaukee, Wisconsin, 53226-3522, United States

  • UCSD

    La Jolla, California, 92037-1300, United States

  • University of Louisville - Hospital

    Louisville, Kentucky, 40202-3700, United States

  • University of Miami - Leonard M. Miller School of Medicine

    Miami, Florida, 33136-1005, United States

  • University of South Florida

    Tampa, Florida, 33606-3601, United States

Conditions

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