New hope for lung cancer patients who stopped responding to targeted pills

NCT ID NCT05870319

First seen Nov 17, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tests a new drug called SKB264 against standard chemotherapy in 376 adults with advanced non-squamous lung cancer that has a specific EGFR gene change and has stopped responding to targeted therapy. The goal is to see if SKB264 alone can help people live longer without their cancer growing. Participants are randomly assigned to receive either SKB264 or chemo, and the study is open-label, meaning both doctors and patients know which treatment is given.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.