Targeted radiation drug takes aim at bone metastases in advanced cancer

NCT ID NCT07087197

First seen Sep 30, 2025 · Last updated Jun 20, 2026 · Updated 29 times

Summary

This early-stage trial is testing a new drug called SKB107, which delivers radiation directly to bone tumors. It is for people with advanced solid tumors (like breast, prostate, or lung cancer) that have spread to the bones and who have run out of standard treatment options. The study will enroll about 90 participants to check the drug's safety, how it moves through the body, and whether it can slow bone tumor growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SKB107 (a radioactive drug that targets bone)

What this could lead to

If it works, this could provide a new treatment option for people with advanced cancer that has spread to the bones, potentially slowing bone tumor growth.

What could go wrong

This is an early Phase 1 trial with only 90 participants, so safety and effectiveness are not yet proven. The radioactive drug may cause side effects like bone marrow suppression or damage to healthy organs.

Conditions

The condition(s) this trial relates to.

metastatic carcinoma in the bone metastatic malignant neoplasm metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.