Smart therapy for young brain tumor patients aims to boost survival and protect thinking skills

NCT ID NCT05535166

First seen Jan 23, 2026 · Last updated Apr 30, 2026 · Updated 17 times

Summary

This study tests whether tailoring treatment based on the tumor's genetic makeup can improve outcomes for children under 5 with medulloblastoma. About 130 participants will receive different combinations of chemotherapy and, in some cases, radiation. The goal is to increase survival while preserving cognitive function and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • C.S. MOTT Children's Hospital, University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital and Clinics of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55404, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cook Children's Medical Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lucille Packard Children's Hospital Stanford

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Orlando Health Arnold Palmer Hospital for Children

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Primary Children's Hospital

    RECRUITING

    Salt Lake City, Utah, 84113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Joseph's Children's Hospital

    RECRUITING

    Tampa, Florida, 33607, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77477, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UT Southwestern Medical Center/Harold C Simmons Comprehensive Cancer Center

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.