Diabetes drug shows promise against deadly brain tumors

NCT ID NCT07541781

First seen May 01, 2026 · Last updated Jun 12, 2026 · Updated 12 times

Summary

This early-phase trial tests whether sitagliptin, a common diabetes medicine, can help treat a severe type of brain cancer (grade 4 glioma) that has returned after standard treatment. About 45 adults will receive sitagliptin along with the standard drug bevacizumab. The study aims to find the safest dose and check if the combination reduces certain immune cells that may help the tumor grow.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Iowa Health Care

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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