Gene test reveals who benefits from diabetes drug
NCT ID NCT04323189
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 32 times
Summary
This pilot study looks at how the diabetes drug sitagliptin affects people who naturally have lower levels of the DPP4 enzyme due to their genes. Researchers will compare 20 adults with and without this genetic trait to see changes in blood sugar and enzyme activity after a meal. The goal is to understand why some people respond differently to the drug, not to test a new treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.