New antibody could reduce bleeding after stroke
NCT ID NCT05948566
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called TS23, an antibody that may help people recover from ischemic strokes by lowering the chance of bleeding in the brain. The trial involves 300 adults who have had a stroke and will receive either the drug or a placebo. Researchers will check for bleeding and measure stroke severity to see if the drug is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TS23 (monoclonal antibody)
- What this could lead to
- If successful, this could lead to a new treatment that helps people recover better from ischemic strokes by reducing the risk of bleeding in the brain.
- What could go wrong
- This is an early Phase 2 trial, so the drug may not prove safe or effective. There is also a risk that the antibody could cause bleeding or other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Ascension Columbia St. Mary's Hospital
RECRUITINGMilwaukee, Wisconsin, 53211, United States
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Ascension St. John
RECRUITINGTulsa, Oklahoma, 74104, United States
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Banner University Medical Center
RECRUITINGPhoenix, Arizona, 85006, United States
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Banner University Medical Center - Tucson
NOT_YET_RECRUITINGTucson, Arizona, 85719, United States
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Baptist Healthcare System, Inc.
RECRUITINGLexington, Kentucky, 40503, United States
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Barnes Jewish Hospital
RECRUITINGSt Louis, Missouri, 63110, United States
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Buffalo General Medical Center
WITHDRAWNBuffalo, New York, 14203, United States
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Christiana Hospital
RECRUITINGNewark, Delaware, 19718, United States
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Duke University Hospital
RECRUITINGDurham, North Carolina, 27710, United States
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Grady Memorial Hospital
RECRUITINGAtlanta, Georgia, 30303, United States
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Harborview Medical Center
RECRUITINGSeattle, Washington, 98104, United States
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Hartford Hospital
RECRUITINGHartford, Connecticut, 06102, United States
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JFK Medical Center
RECRUITINGEdison, New Jersey, 08837, United States
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Jackson Memorial Hospital
RECRUITINGMiami, Florida, 33136, United States
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Kaiser Permanente Los Angeles
RECRUITINGLos Angeles, California, 90027, United States
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M Health Fairview Ridges Hospital
RECRUITINGBurnsville, Minnesota, 55337, United States
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M Health Fairview Southdale Hospital
RECRUITINGEdina, Minnesota, 55435, United States
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M Health Fairview University of Minnesota Medical Center
RECRUITINGMinneapolis, Minnesota, 55455, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02171, United States
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Mayo Clinic Phoenix
WITHDRAWNPhoenix, Arizona, 85054, United States
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Medical University of South Carolina University Hospital
RECRUITINGCharleston, South Carolina, 32608, United States
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Memorial Hermann Texas Medical Center
RECRUITINGHouston, Texas, 77030, United States
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Methodist University Hospital
RECRUITINGMemphis, Tennessee, 38104, United States
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Mount Sinai West
RECRUITINGNew York, New York, 10029, United States
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NYP Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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NYU Langone Health
RECRUITINGBrooklyn, New York, 11220, United States
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North Shore University Hospital
RECRUITINGManhasset, New York, 11030, United States
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OSU Wexner Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
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Prisma Health Greenville Memorial
RECRUITINGGreenville, South Carolina, 29605, United States
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Providence St. Vincent Medical Center
RECRUITINGPortland, Oregon, 97225, United States
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Rhode Island Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
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SUNY Upstate Medical University
RECRUITINGSyracuse, New York, 13202, United States
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Saint Luke's Hospital of Bethlehem Pennsylvania
RECRUITINGBethlehem, Pennsylvania, 18015, United States
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Sutter Medical Center
WITHDRAWNSacramento, California, 95816, United States
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Temple University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
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The Mount Sinai Hospital
RECRUITINGNew York, New York, 10029, United States
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UCSD Health La Jolla
RECRUITINGLa Jolla, California, 92093, United States
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UCSD Medical Center- Hillcrest Hospital
RECRUITINGSan Diego, California, 92103, United States
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UF Health Shands Hospital
TERMINATEDGainesville, Florida, 32608, United States
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UVA Medical Center
RECRUITINGCharlottesville, Virginia, 22901, United States
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United Hospital
WITHDRAWNSaint Paul, Minnesota, 55102, United States
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University of Alabama Hospital
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Cincinnati Medical Center
RECRUITINGCincinnati, Ohio, 45267, United States
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University of Iowa Hospitals & Clinics
WITHDRAWNIowa City, Iowa, 52242, United States
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University of Louisville Hospital
RECRUITINGLouisville, Kentucky, 40202, United States
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University of Utah Healthcare
WITHDRAWNSalt Lake City, Utah, 84132, United States
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VCU Medical Center
WITHDRAWNRichmond, Virginia, 23298, United States
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Wake Forest Baptist Medical Center
TERMINATEDWinston-Salem, North Carolina, 27157, United States
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Westchester Medical Center
NOT_YET_RECRUITINGValhalla, New York, 10595, United States
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Yale New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06511, United States
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More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Stroke care at a distance: can video consultations speed up Life-Saving treatment?
- New risk score could predict strokes in heart patients despite blood thinners
- Stroke recovery videos redesigned with symbols may boost daily living and sleep
- AI and ultrasound join forces to spot muscle wasting in Brain-Injured ICU patients
- Brain scans could reveal hidden stroke risk in artery disease patients
- Robotic glove may help stroke survivors regain hand control