Can a molecule that boosts cell energy reach the brain in Alzheimer's?

NCT ID NCT05040321

First seen Mar 24, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This early-stage study tests whether a daily pill called MIB-626 can enter the brain and affect aging-related pathways in people with mild Alzheimer's disease. Researchers will measure the drug and its byproducts in spinal fluid and use advanced brain scans to see if it boosts NAD, a key energy molecule. The study involves 22 participants aged 55 to 85 with confirmed Alzheimer's pathology. The goal is to gather evidence for future, larger trials, not to treat the disease directly.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115-0000, United States

Conditions

Explore the condition pages connected to this study.