Can a pill slow aging? small trial tests sirolimus in seniors

NCT ID NCT05237687

Recruiting now Disease control Sponsor: Irina Timofte Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial is testing whether the drug sirolimus can slow aging in adults aged 65 to 80. Ten participants will be randomly assigned to receive sirolimus or standard care, and researchers will measure aging biomarkers like walking speed and cellular changes after one year. The goal is to see if sirolimus can reduce age-related decline and prevent chronic diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sirolimus (a drug that may slow aging at the cellular level)
What this could lead to: If it works, this could point toward a treatment that delays aging and reduces chronic diseases like skin cancer.
What could go wrong: This is a very small early-phase trial with only 10 participants, so results may not apply to everyone. Sirolimus is an immunosuppressant and can have side effects like increased infection risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AGING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING

Contacts and locations

Locations

UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.