Can a pill slow aging? small trial tests sirolimus in seniors

NCT ID NCT05237687

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial is testing whether the drug sirolimus can slow aging in adults aged 65 to 80. Ten participants will be randomly assigned to receive sirolimus or standard care, and researchers will measure aging biomarkers like walking speed and cellular changes after one year. The goal is to see if sirolimus can reduce age-related decline and prevent chronic diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sirolimus (a drug that may slow aging at the cellular level)

What this could lead to

If it works, this could point toward a treatment that delays aging and reduces chronic diseases like skin cancer.

What could go wrong

This is a very small early-phase trial with only 10 participants, so results may not apply to everyone. Sirolimus is an immunosuppressant and can have side effects like increased infection risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact