Promising combo aims to tame relapsed childhood cancers
NCT ID NCT02574728
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a daily combination of sirolimus, celecoxib, and low-dose chemotherapy in 46 children whose solid or brain tumors have returned or not responded to standard treatment. The goal is to see if this approach can shrink tumors or stop them from growing. While not a cure, it offers a potential way to control the disease and manage symptoms.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Healthcare of Atlanta, Scottish Rite
Atlanta, Georgia, 30342, United States
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Children's Healthcare of Atlanta-Egleston
Atlanta, Georgia, 30322, United States
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Children's Mercy Hospital
Kansas City, Missouri, 64108, United States
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Nemours/Alfred I. duPont Hospital for Children
Wilmington, Delaware, 19803, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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University of Virginia Health System
Charlottesville, Virginia, 22908, United States