New drug dosing study aims to preserve insulin in type 1 diabetes
NCT ID NCT05574335
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 33 times
Summary
This study tested four different doses of a drug called siplizumab in people aged 8 to 45 who were diagnosed with type 1 diabetes within the last 18 months. The goal was to find a safe dose that could help preserve the body's ability to produce insulin by changing certain immune cells. Participants received weekly doses for 12 weeks and were followed for up to a year to monitor safety and insulin production.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Benaroya Research Institute at Virginia Mason: Diabetes Research Program
Seattle, Washington, 98101, United States
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Columbia University Medical Center: Naomi Berrie Diabetes Center
New York, New York, 10032, United States
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University of Colorado School of Medicine: Barbara Davis Center for Diabetes
Aurora, Colorado, 80045, United States
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University of Iowa Children's Hospital: Department of Pediatrics, Pediatric Endocrinology and Diabetes
Iowa City, Iowa, 52242, United States
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University of Texas Southwestern Medical Center: Department of Internal Medicine, Division of Endocrinology
Dallas, Texas, 75390, United States
Conditions
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