New gel could boost recovery after sinus surgery

NCT ID NCT07383402

Not yet recruiting Disease control Sponsor: Amin Javer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests a gel containing povidone-iodine and budesonide that is placed inside the sinuses right after endoscopic sinus surgery. The goal is to see if it reduces inflammation and scarring better than a placebo gel. The study will involve 180 adults with chronic rhinosinusitis and will measure healing at 12 weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Povidone-iodine and budesonide gel-forming suspension
What this could lead to: If it works, this gel could reduce inflammation and scarring after sinus surgery, leading to better long-term outcomes for people with chronic sinusitis.
What could go wrong: This is a phase 3 trial, but it is not yet recruiting. The gel is applied during surgery, so results may vary, and some people may have allergic reactions to povidone-iodine.

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC RHINOSINUSITIS (CRS)

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

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